PGxCheck...What is our DNA saying?




We need to consider how genetic information

can help us with respect to healthcare. We are able to perform genetic testing more readily,

but how are we using the results? Join in the discussion!


Personalized medicine and pharmacogenomics (the influence of genetics on drugs) is here. It is in its infancy and we all will watch it grow. From healthcare professionals to the general public, pharmacogenomics and the broader area of personalized medicine will present a learning curve.

This blog is made possible through an individual making their genetic information available. 

As we learn what this individual's genetics are telling us...and what it is not telling us, we will discuss it. I am sure there will be many questions. We will have individuals from pharmacy, genetics, ethics, law, and other disciplines adding their expertise and thoughts to the discussion. I sincerely hope you will contemplate the information, formulate your thoughts, and participate in the discussion!

The Breadth of Personalized Medicine - Personal Genome Evaluation

Personal genome evaluation (PGE) is a growing approach to understanding the influence of genetics on an individual's health. We have talked about a number of topics related to PGE, such as recently bringing up drug-gene interactions as a part of pharmacogenetics, but there is a broader context.

While drug-gene interactions are a component of pharmaco (drug) genetics, many other "pieces of the pie" make up the whole of personalized medicine. 

Consider the following as "pieces of the personalized medicine pie":

1. Medical education

2. Health care information technology

3. Regulation (policy)

4. Technology and tools

5. Insurance coverage and reimbursement

6. Genetic privacy and legal protections

Give us your thoughts on how these individual "pieces" help to make the "whole pie". Click on the title to check out this important document: 

Read about the given pieces mentioned above and comment as to why you feel one of more pieces are critical. Let's hear your thoughts!!!

5 comments | Add a New Comment
1. Myranda Smith | November 04, 2013 at 02:01 PM EST

One of the biggest issues I see here in trying to make Personalized Medicine happen is trying to get the insurance companies on board. At this time it is hard to find an insurance company that is likely to cover most of the average persons need, let alone be affordable for everyone to obtain. Also, even with the new health care act being implemented by the Obama Administration, will there be room for coverage when personalized medicine is concerned?

2. Katlyn Brown | November 04, 2013 at 08:01 PM EST

Personalized medicine has multiple parts as stated above. I think that the first issue that needs addressed is medical education. This is critical because if the physican does not fully understand personalized medicine or is not comfortable talking about it how will the patient learn by asking questions if the doctor does not know the answers ? While the current medical students are experiencing more classes related to personalized medicine and will be able to help in the future, current doctors and other medical personal lack this understanding and knowledge because it is new to them. To fix this piece of the pie medical personal should have more Continuing Education courses to help update them on personalized medicine so that they know the most they can about this new area of medicine and can help thier patients to the fullest. I also agree wtih Myranda that a major hurdle to overcome will be getting insurance companies on board while the cost is affordable.

3. Victoria Downey | November 05, 2013 at 02:49 PM EST

I think a a very important factor is the physician's medical education. There has been a lack of genetic education which has lead to a lack of confidence when testing for ovarian cancer. This is a big problem. It is imperative that those who are diagnosing patients with illnesses are confident in what they are telling the patient.

4. Jasmine Hossler | November 05, 2013 at 09:52 PM EST

I think the most important will be patient medical education on the subject. If a patient does not understand the importance or benefit of using personalized medicine they might not see the point in the extra cost associated with personalized medicine.

5. Alexandria Lacombe | November 06, 2013 at 01:18 PM EST

I believe that the biggest issue will be genetic privacy. New laws will more than likely have to be put into place outlawing genetic discrimination and allowing people to keep their genetic information 'for their eyes only'. It might be a difficult task to get legislatures educated and on board (which also ties into the education piece).

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