By DFK | January 22, 2013 at 09:42 AM EST | 28 comments
I explained to JES, our 'DNA data donator', how I went about getting my DNA tested last year and how I intended to use the data as the basis for an elective course called 'personal genome evaluation'. I knew that if we offered this course again, that we would need a different set of data to look at...so, JES offered his DNA data. We will get to JES's information soon.
As I posted last year and have now 'edited', I now describe what JES did to get his DNA tested.
JES went online, and reviewed the 23andme procedure for providing a DNA sample. He, picked the service and paid via credit card, then waited for the kit to arrive. In about a week, he received the test sample kit and promptly read the directions. Following the directions, JES provided a saliva sample of about 5 mL, a teaspoonful, which took about five minutes of spitting into the tube to obtain this volume. The tube cap had a preservative that automatically mixed with the saliva when the cap is screwed on the tube and the 'snapped' closed. JES inverted the tube a number of times to mix the saliva and preservative. At this point he replaced to first cap with the shipping cap. He placed the capped tube with the saliva sample in the provided zip-lock 'bio-hazard-bag' and placed that into the already addressed return container.
The fact that saliva was used is key to a consumer product. With DNA in every nucleated cell (i.e., cells with a nucleus) of the body I guess it really doesn't matter what sample you provide...I just do not see the public drawing a blood sample and getting white blood cells that way (remember red blood cells won't help here...no DNA)! And, I, and others would struggle supplying a sufficient hair sample!
JES and I discussed the 'point of no return' point, i.e., putting the shipping carton with the saliva sample in the mail. JES did not hesitate at all. He had seen my data and wanted to see his. He would receive information about his physical traits, risk of disease, 'drug sensitivity', and disease carrier status. JES and I discussed his deciding to get his DNA tested and I thought 'go ahead the DNA is there regardless of whether or not you know what is says'. This is the same thing I thought about my own testing last year. So, into the mailbox it went.
It did take about a month for the results to be made available to JES via the 23andme.com website.
We are going to start with the simple things, what JES's DNA states about his physical traits. Take a look at 'About JES'. Check the link on the menu at the left. A question comes to my mind right away: 1. I have seen JES sneeze when he is in the sun light. I don't think it is just the occasional sneeze. Anyhow, look at his trait information and I will add one more here...JES has a lower tendency to overeat...wish I did!
So, to get started just look at JES's traits. I will say that his genetics do not exactly match his expressed traits (phenotype). Why would this be possible? Go ahead and post your thoughts!